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TXA is showing a positive impact in severe traumatic hemorrhage. So how does it work? Original Article : https://www.jems.com/2018/01/01/an-interdisciplinary-literature-review-of-prehospital-use-of-tranexamic-acid-txa-in-major-bleeding/ An Interdisciplinary Literature Review of Prehospital Use of Tranexamic Acid (TXA) in Major Bleeding *This video was made to supplement the original JEMS - Emergency Medical Services article https://www.jems.com/2018/01/01/an-interdisciplinary-literature-review-o
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🩸 Tranexamic Acid (TXA) – How does it actually work? When trauma patients bleed, their body forms clots to stop the loss. But the body also activates fibrinolysis – the natural breakdown of clots. In major haemorrhage this can become overactive, leading to clot breakdown before bleeding is controlled. 👉 TXA works by blocking plasminogen from converting into plasmin, the enzyme that dissolves fibrin clots. 👉 This helps stabilise clots, reduce bleeding, and improve survival if given within 3 ho
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