Hepatocellular carcinoma (HCC) is a major global health issue, with significant morbidity and mortality rates. As the sixth most common cancer and the third leading cause of cancer-related deaths, HCC ...

The U.S. Food and Drug Administration (FDA) has cleared an investigational new drug application from FluoGuide A/S in Copenhagen, Denmark, allowing the company to move forward in the U.S. with a ...

As many as 40% of lumpectomies leave positive margins that necessitate a second surgery, but a novel fluorescent imaging agent used along with a direct visualization system may improve complete ...

Fluorescence-guided lymphadenectomy after neoadjuvant chemotherapy was linked to improved survival in gastric cancer. It was also significantly associated with more retrieved lymph nodes. The 3-year ...

Successful surgery for head and neck squamous cell carcinoma (HNSCC) relies upon complete tumor removal and safe preservation of the fragile nerves in the vicinity. Both are challenging. Fluorescence ...

Accurate removal of tumors is the most critical aspect of cancer surgery, yet it remains a significant challenge in clinical practice. In breast cancer, for example, the positive margin rate—where ...

When surgeons dissect tissue to remove a tumor or make a repair, they must work cautiously, relying on electrophysical monitors and their own anatomical knowledge to avoid cutting nerves, which could ...

Figure 1: Panel of various pediatric tumors comparing H&E staining, FRα, and FRβ protein expression within the tumor. None of these tumors demonstrate FRα expression; however all of the tumors ...

The final report of a phase I trial of surgical resection with biodegradable carmustine (BCNU) wafer placement followed by vaccination with dendritic cells pulsed with tumor lysate for patients with ...

For the first time, a fluorescent-guided nerve imaging agent shows promise for use in humans, according to a paper published in Nature Communications. The study sought to evaluate the safety of ...