siMecA-AGO2 complex inhibits the translation of the mecA gene which encodes the penicillin-binding protein 2a (PBP2a), a protein at the heart of the drug-resistance phenotype in MRSA. By reducing ...
Methicillin-resistant Staphylococcus aureus (MRSA) pneumonia is a well-recognized cause of bacterial pneumonia, resulting in increased morbidity and mortality worldwide. Traditional antibiotics face ...
Proteins form the structural and functional backbone of the cell, and any perturbation in their synthesis can disrupt normal cellular functions. The DNA blueprint is carefully read, transcribed, and ...
At the Vrije Universiteit Brussel (VUB)—Flanders Institute for Biotechnology (VIB), biologist Jessie Vandierendonck has been investigating new, alternative treatments to combat bacterial infections ...